A mechanism of augmentation of in vitro antibody response by 2-mercaptoethanol in murine lymphocytes

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Mechanism of augmentation of the antibody response in vitro by 2- mercaptoethanol in murine lymphocytes. I. 2-Mercaptoethanol-induced stimulation of the uptake of cystine, an essential amino acid

The mechanism of augmentation of the primary antibody response in vitro by 2-mercaptoethanol (2-ME) was investigated. By using cystine-free RPMI 1640 medium, it was demonstrated that cyst(e)ine was absolutely required for eliciting the following murine lymphocyte reactions: antibody response to sheep erythrocytes, proliferative response to concanavalin A or lipopolysaccharide (LPS), and polyclo...

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ژورنال

عنوان ژورنال: Ensho

سال: 1982

ISSN: 0389-4290,1884-4006

DOI: 10.2492/jsir1981.2.2_151